Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366768 | 0.93 | KDM4E (0.42) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL365501 | 0.87 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL366597 | 0.86 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL365059 | 0.85 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL365806 | 0.84 | MAPT (0.38) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL364522 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL364747 | 0.82 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL366380 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL364461 | 0.81 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTMEN1APAF1 | |
| SCHEMBL366329 | 0.80 | KDM4E (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |