Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365361 | 0.90 | PPARG (0.49) | KDM4E | |
| SCHEMBL366327 | 0.84 | MAPT (0.63) | KDM4E | |
| SCHEMBL365439 | 0.83 | KDM4E (0.48) | KDM4E | |
| SCHEMBL365062 | 0.82 | TSHR (0.42) | — | |
| SCHEMBL364682 | 0.81 | KMT2A (0.58) | KDM4E | |
| SCHEMBL365132 | 0.81 | ALDH1A1 (0.46) | KDM4E | |
| SCHEMBL364758 | 0.81 | MEN1 (0.44) | KDM4E | |
| SCHEMBL366943 | 0.81 | KDM4E (0.46) | KDM4E | |
| SCHEMBL364878 | 0.80 | SMN1; SMN2 (0.55) | KDM4E | |
| SCHEMBL365760 | 0.80 | KDM4E (0.53) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |