Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HLCS | P50747 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883179 | 0.98 | MAPT (0.55) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL10794719 | 0.94 | MAPT (0.59) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL1036088 | 0.79 | CYP1A2 (0.46) | MAPTCYP1A2KMT2AMEN1HTT | |
| SCHEMBL10704088 | 0.77 | CYP1A2 (0.48) | MAPTCYP1A2KMT2AMEN1HLCS | |
| SCHEMBL11861937 | 0.77 | CYP1A2 (0.48) | MAPTCYP1A2KMT2AMEN1HLCS | |
| SCHEMBL5612700 | 0.76 | MAPT (0.70) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL8076491 | 0.75 | TP53 (0.47) | MAPTCYP1A2KMT2AMEN1HLCS | |
| SCHEMBL9799080 | 0.73 | CYP1A2 (0.50) | MAPTCYP1A2KMT2AMEN1HTT | |
| SCHEMBL6742596 | 0.73 | TP53 (0.46) | MAPTCYP1A2KMT2AMEN1HLCS | |
| SCHEMBL8154627 | 0.73 | MAPT (1.00) | MAPTCYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020168-A2 | BIO-RENEWABLE POLYMERS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-25 | — | — | WO | disclosed |
| EP-2146967-A2 | TETRAHYDROINDOLE AND TETRAHYDROINDAZOLE DERIVATIVES | Serenex, Inc. (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008130879-A2 | TETRAHYDROINDOLE AND TETRAHYDROINDAZOLE DERIVATIVES | SERENEX, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080269193-A1 | Tetrahydroindole and Tetrahydroindazole Derivatives | SERENEX, INC. | 2008-10-30 | — | — | US | disclosed |
| US-6765089-B1 | FOR USE IN THE SYNTHESIS OF PEPTIDES, OLIGOSACCHARIDES, GLYCOPEPTIDES AND GLYCOLIPIDS | ALCHEMIA PTY LTD (AU) | 2004-07-20 | — | — | US | disclosed |
| EP-1017683-A4 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | ALCHEMIA PTY LTD (AU) | 2002-03-06 | — | — | EP | disclosed |
| EP-1017683-A1 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | Alchemia Pty. Ltd. (AU) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015510-A1 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | ALCHEMIA PTY. LTD. (AU) | 1999-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269193-A1 | Tetrahydroindole and Tetrahydroindazole Derivatives | HSF1, HSP90AB1, TPH1 | MAPT 356/4885CYP1A2 102/4885CYP2C9 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.