Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669348 | 0.80 | CRHR1 (0.31) | PIK3CDF10CRHR1 | |
| SCHEMBL14763123 | 0.70 | MET (0.38) | — | |
| SCHEMBL3675921 | 0.67 | HRH4 (0.31) | — | |
| SCHEMBL16302883 | 0.64 | HPGD (0.36) | — | |
| SCHEMBL3669422 | 0.64 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL3668456 | 0.62 | HRH4 (0.33) | — | |
| SCHEMBL3670855 | 0.61 | HRH4 (0.33) | — | |
| SCHEMBL3771728 | 0.60 | TSHR (0.32) | — | |
| SCHEMBL3666328 | 0.59 | BACE1 (0.36) | — | |
| SCHEMBL25304003 | 0.58 | AOC3 (0.49) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139478-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Cytokinetics, Incorporated (US) | 2010-01-06 | — | — | EP | claimed |
| WO-2008121333-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-10-09 | — | — | WO | claimed |