Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669877 | 0.80 | HRH4 (0.33) | TSHRRECQLGUSBKMO | |
| SCHEMBL3771728 | 0.78 | TSHR (0.32) | TSHRRECQL | |
| SCHEMBL3669613 | 0.78 | HRH4 (0.33) | TSHRRECQLGUSBKMO | |
| SCHEMBL3672734 | 0.78 | HRH4 (0.33) | TSHRRECQLGUSBKMO | |
| SCHEMBL3670194 | 0.78 | HRH4 (0.33) | TSHRRECQLGUSBKMO | |
| SCHEMBL2300295 | 0.78 | HRH4 (0.33) | TSHRRECQLGUSBKMO | |
| SCHEMBL3675423 | 0.78 | HRH4 (0.33) | TSHRRECQLGUSBKMO | |
| SCHEMBL3668593 | 0.75 | HRH4 (0.36) | TSHRRECQLGUSB | |
| SCHEMBL3672288 | 0.72 | BACE1 (0.34) | TSHRRECQLGUSB | |
| SCHEMBL3667535 | 0.72 | BACE1 (0.34) | TSHRRECQLGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851484-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2010-12-14 | — | — | US | claimed |
| EP-2139478-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Cytokinetics, Incorporated (US) | 2010-01-06 | — | — | EP | claimed |
| WO-2008121333-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-10-09 | — | — | WO | claimed |
| US-20080242695-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INC. | 2008-10-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242695-A1 | Certain Chemical Entities, Compositions, and Methods | TNNC1, TNNI3, TNNT2 | TSHR 647/4885RECQL 1932/4885GUSB 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.