SCHEMBL3667309

SCHEMBL3667309

CC(Cc1ccccc1)(Cc1ccccc1Cl)NC(N)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
CYP1A2 P05177 1/20 0.42
RECQL P46063 1/20 0.42
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
PLAAT3 P53816 2/20 0.39
PLAAT5 Q96KN8 2/20 0.39
PLAAT2 Q9NWW9 2/20 0.39
PLAAT4 Q9UL19 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
HIF1A Q16665 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
GFER P55789 1/20 0.38
MMP1 P03956 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9696386 0.71 BLM (0.49) CYP3A4CYP1A2RECQLALDH1A1RAB9A
SCHEMBL3763588 0.71 KCNJ6 (0.44) CYP3A4CYP1A2ALDH1A1CYP2C9CYP2C19
SCHEMBL8179700 0.70 SMN1; SMN2 (0.41) RAB9ANPC1SMN1; SMN2TP53
SCHEMBL9547513 0.70 SMN1; SMN2 (0.52) CYP3A4CYP1A2RECQLMAPK1ALDH1A1
Hydrochloric Acid SCHEMBL27858949 0.70 PKM (0.43) CYP3A4CYP2C9CYP2C19RAB9ANPC1
SCHEMBL3141470 0.69 CYP3A4 (0.47) CYP3A4CYP1A2ALDH1A1CYP2C9CYP2C19
SCHEMBL11748890 0.69 CYP3A4 (0.47) CYP3A4CYP1A2RECQLMAPK1ALDH1A1
SCHEMBL11655669 0.69 THRA (0.38) CYP3A4CYP1A2RECQLMAPK1ALDH1A1
SCHEMBL28400092 0.69 NPC1 (0.41) ALDH1A1RAB9ANPC1L3MBTL1SMN1; SMN2
SCHEMBL28834581 0.69 CYP2C19 (0.43) CYP3A4CYP1A2CYP2C19RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2180789-A2 IMPROVED PROCESSES FOR THE CONTROL OF UNDESIRED VEGETATION Gowan Co. (US) 2010-05-05 EP disclosed
WO-2009015064-A2 IMPROVED PROCESSES FOR THE CONTROL OF UNDESIRED VEGETATION GOWAN CO. (US) 2009-01-29 WO disclosed