Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760761 | 0.82 | FABP4 (0.55) | FABP4POLBHPGDALDH1A1KDM4E | |
| SCHEMBL1467305 | 0.81 | FABP4 (0.56) | FABP4KDM4EFABP3GAANPC1 | |
| SCHEMBL81434 | 0.81 | POLB (0.75) | POLBHPGDALDH1A1KDM4EGAA | |
| SCHEMBL29521664 | 0.81 | POLB (0.75) | POLBHPGDALDH1A1KDM4EGAA | |
| SCHEMBL29892467 | 0.79 | MAPT (0.61) | POLBALDH1A1KDM4EGAANPC1 | |
| SCHEMBL1140606 | 0.79 | MAPT (0.61) | POLBALDH1A1KDM4EGAANPC1 | |
| Hydrochloric Acid SCHEMBL27918048 | 0.79 | POLB (0.72) | POLBHPGDALDH1A1KDM4EGAA | |
| Phosphine SCHEMBL30387635 | 0.79 | POLB (0.72) | POLBHPGDALDH1A1KDM4EGAA | |
| SCHEMBL14889779 | 0.78 | POLB (0.56) | POLBHPGDALDH1A1KDM4EGAA | |
| SCHEMBL25421397 | 0.77 | CA1 (0.49) | KDM4EGAAIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593226-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | Abbvie Inc. (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012009698-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |