Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498625 | 0.84 | KMT2A (0.64) | KMT2AALDH1A1POLBCYP2C19ELANE | |
| SCHEMBL28555671 | 0.83 | PTGS1 (0.56) | KMT2AALDH1A1TSHRTP53POLB | |
| SCHEMBL7449653 | 0.79 | ALDH1A1 (0.49) | KMT2AALDH1A1CYP2C19ARLMNA | |
| SCHEMBL1773733 | 0.75 | CYP2C19 (0.39) | KMT2AALDH1A1CYP2C19ELANE | |
| SCHEMBL28552779 | 0.72 | AR (0.54) | KMT2AALDH1A1TP53POLBCYP2C19 | |
| SCHEMBL25137282 | 0.71 | HDAC6 (0.56) | KMT2ACYP2C19ELANEARLMNA | |
| SCHEMBL17160621 | 0.71 | KMT2A (0.55) | KMT2AALDH1A1TSHRTP53POLB | |
| SCHEMBL28550434 | 0.71 | AR (0.56) | KMT2AALDH1A1POLBCYP2C19AR | |
| SCHEMBL8030958 | 0.70 | ELANE (0.46) | ELANEAR | |
| SCHEMBL28556498 | 0.70 | ALDH1A1 (0.60) | KMT2AALDH1A1POLBARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242747-A1 | SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | Sanofi-Aventis (FR) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009097997-A1 | SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |