Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.82 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.82 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.82 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.82 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.82 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.82 |
| ▸ | GMNN | O75496 | 1/20 | 0.80 |
| ▸ | APEX1 | P27695 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16496191 | 0.93 | LMNA (0.78) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL3665228 | 0.93 | USP2 (0.76) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL9430960 | 0.93 | USP2 (0.76) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL9431542 | 0.91 | LMNA (0.83) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL3667503 | 0.90 | LMNA (0.73) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| Pirenzepine SCHEMBL41705 | 0.90 | LMNA (1.00) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| Pirenzepine SCHEMBL30553045 | 0.90 | LMNA (1.00) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| Pirenzepine SCHEMBL9254860 | 0.90 | LMNA (1.00) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| Pirenzepine SCHEMBL29793172 | 0.90 | LMNA (1.00) | LMNAUSP2ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL10971915 | 0.89 | LMNA (0.80) | LMNAUSP2ALDH1A1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238248-A2 | A METHOD FOR GENERATING A RECOMBINANT CLONAL CELL LINE AND NOVEL REAGENTS FOR USE IN THE METHOD | Cellaura Technologies LTD (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009040555-A2 | A METHOD FOR GENERATING A RECOMBINANT CLONAL CELL LINE AND NOVEL REAGENTS FOR USE IN THE METHOD | CELLAURA TECHNOLOGIES LTD (GB) | 2009-04-02 | — | — | WO | disclosed |
| US-5324832-A | Muscarinic antagonists | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-06-28 | — | — | US | disclosed |
| WO-1993000906-A1 | MUSCARINIC ANTAGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-01-21 | — | — | WO | disclosed |