Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 4/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | EIF4E | P06730 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659569 | 0.89 | PDK2 (0.35) | CA1CA2PDK2 | |
| SCHEMBL20548197 | 0.88 | PDK2 (0.41) | NR3C2RECQLCA1CA2XDH | |
| SCHEMBL737462 | 0.87 | PDE3B (0.36) | RECQLCA1CA2 | |
| SCHEMBL737417 | 0.87 | RARB (0.35) | NR3C2RECQLCA1CA2SLC22A12 | |
| SCHEMBL739992 | 0.86 | CA1 (0.33) | RECQLCA1CA2PKMPDK2 | |
| SCHEMBL2015655 | 0.86 | CA1 (0.35) | RECQLCA1CA2PKMPDK2 | |
| SCHEMBL2014009 | 0.86 | RXRB (0.41) | RECQLCA1CA2PKMPDK2 | |
| SCHEMBL737165 | 0.86 | KDM4E (0.37) | RECQLCA1CA2PKMPDK2 | |
| SCHEMBL12274098 | 0.86 | RXRB (0.41) | RECQLCA1CA2PKMPDK2 | |
| SCHEMBL362701 | 0.86 | RXRB (0.41) | RECQLCA1CA2PKMPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140080877-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2014-03-20 | — | — | US | disclosed |
| US-8623896-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| EP-2592079-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2013-05-15 | — | — | EP | disclosed |
| EP-2518068-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2012-10-31 | — | — | EP | disclosed |
| EP-2238132-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-01 | — | — | EP | disclosed |
| US-20100279999-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2238132-A2 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009080250-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279999-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | NR3C2 3844/4885RECQL 804/4885CA1 614/4885 |
| US-20140080877-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | NR3C2 3866/4885RECQL 799/4885CA1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.