Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.53 |
| ▸ | RAB9A | P51151 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713986 | 0.91 | NPC1 (0.62) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL30083 | 0.91 | NPC1 (0.62) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL12306756 | 0.89 | NPC1 (0.60) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL5823988 | 0.89 | NPC1 (0.60) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL12354585 | 0.88 | S1PR1 (0.61) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL12306751 | 0.86 | NPC1 (0.60) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL11635661 | 0.86 | NPC1 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL1421139 | 0.85 | S1PR1 (0.58) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL12309409 | 0.85 | NPC1 (0.63) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL19072498 | 0.85 | NPC1 (0.55) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234991-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | Georgia Tech Research Corporation (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009080797-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |