Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713986 | 0.98 | NPC1 (0.62) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL3668075 | 0.89 | NPC1 (0.53) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL1104799 | 0.89 | NPC1 (0.72) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL6296907 | 0.89 | NPC1 (0.72) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL3293191 | 0.87 | NPC1 (0.75) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL2623780 | 0.87 | NPC1 (0.75) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL445400 | 0.83 | KIF11 (0.56) | NPC1RAB9AKDM4EKIF11IKBKB | |
| SCHEMBL67105 | 0.83 | KIF11 (0.56) | NPC1RAB9AKDM4EKIF11IKBKB | |
| SCHEMBL74782 | 0.82 | S1PR1 (0.67) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL10330362 | 0.82 | NPC1 (0.64) | NPC1RAB9AKDM4ES1PR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006094101-A1 | MULTILAYER POLYMER LIGHT-EMITTING DIODES FOR SOLID STATE LIGHTING APPLICATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-09-08 | — | — | WO | disclosed |