Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299666 | 0.89 | MEN1 (0.47) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL294292 | 0.88 | MEN1 (0.46) | ALDH1A1HSD17B10KMT2ATP53MAPT | |
| SCHEMBL294568 | 0.87 | MEN1 (0.47) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL295275 | 0.77 | MEN1 (0.50) | ALDH1A1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13068607 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KMT2ACA1CA2 | |
| SCHEMBL3372765 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3373803 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HSD17B10KMT2ACA1CA2 | |
| SCHEMBL3373738 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HSD17B10KMT2ACA1RECQL | |
| SCHEMBL5398574 | 0.70 | ALDH1A1 (0.73) | ALDH1A1HSD17B10KMT2ACA1RECQL | |
| SCHEMBL5404610 | 0.69 | ALDH1A1 (0.71) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240474-B1 | CYCLIC PYRIDYL-N-(1,3,4)-THIADIAZOL-2-YL-BENZENE SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2012-03-14 | — | — | EP | disclosed |