Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401314 | 0.87 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CA1CA2KMT2A | |
| SCHEMBL5404610 | 0.87 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CA1KMT2ALMNA | |
| Glyprothiazol SCHEMBL1814714 | 0.87 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CA1CA2LMNA | |
| SCHEMBL5388827 | 0.87 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CA1CA2KMT2A | |
| SCHEMBL5395237 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CA1CA2KMT2A | |
| SCHEMBL5401322 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CA1CA2KMT2A | |
| SCHEMBL4594513 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CA1CA2KMT2A | |
| Hydrochloric Acid SCHEMBL3776916 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CA1CA2KMT2A | |
| SCHEMBL3788760 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CA1CA2KMT2A | |
| SCHEMBL11893082 | 0.81 | ALDH1A1 (0.77) | ALDH1A1CA1CA2RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173030-B2 | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2007-02-06 | — | — | US | claimed |
| EP-1631558-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE I | BIOVITRUM AB (SE) | 2006-03-08 | — | — | EP | claimed |
| US-20050009821-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB | 2005-01-13 | — | — | US | claimed |
| WO-2004103980-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE I | BIOVITRUM AB (SE) | 2004-12-02 | — | — | WO | claimed |
| US-20070066614-A1 | Ihibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB | 2007-03-22 | — | — | US | disclosed |
| US-7173030-B2 | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2007-02-06 | — | — | US | disclosed |
| EP-1631558-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE I | BIOVITRUM AB (SE) | 2006-03-08 | — | — | EP | disclosed |
| US-20050009821-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB | 2005-01-13 | — | — | US | disclosed |
| WO-2004103980-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE I | BIOVITRUM AB (SE) | 2004-12-02 | — | — | WO | disclosed |
| US-4568752-A | Recording material for color photography | CIBA-GEIGY AG (CH) | 1986-02-04 | — | — | US | disclosed |
| US-4248961-A | YELLOW COUPLER ACHIEVING GOOD COLOR DENSITY | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4238564-A | YELLOW COUPLERS | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009821-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD11B2 | ALDH1A1 53/4885HSD17B10 22/4885CA1 1267/4885 |
| US-20070066614-A1 | Ihibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD17B11 | ALDH1A1 36/4885HSD17B10 16/4885CA1 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.