⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084220 | 0.90 | CHRM2 (0.35) | — | |
| SCHEMBL3089397 | 0.85 | CNR1 (0.35) | — | |
| SCHEMBL3082742 | 0.76 | TP53 (0.43) | — | |
| SCHEMBL3084192 | 0.72 | CNR1 (0.36) | — | |
| SCHEMBL31003728 | 0.71 | CNR1 (0.36) | — | |
| SCHEMBL3092417 | 0.70 | MMP2 (0.39) | — | |
| SCHEMBL3093596 | 0.69 | CNR1 (0.32) | — | |
| SCHEMBL3093775 | 0.69 | MMP2 (0.43) | — | |
| SCHEMBL3078088 | 0.68 | GRIN2B (0.33) | — | |
| SCHEMBL5479452 | 0.68 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139856-A1 | SUBSTITUTED 3-(4-HYDROXYPHENYL)-INDOLIN-2-ONE-COMPOUNDS | Topotarget A/S (DK) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008129075-A1 | SUBSTITUTED 3-(4-HYDROXYPHENYL)-INDOLIN-2-ONE-COMPOUNDS | TOPOTARGET A/S (DK) | 2008-10-30 | — | — | WO | disclosed |