SCHEMBL3668657

SCHEMBL3668657

Cc1cccc(F)c1C(C)(N)N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.46
CD44 P16070 1/20 0.38
KIF11 P52732 1/20 0.35
CYP3A4 P08684 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TRPA1 O75762 1/20 0.33
ATM Q13315 1/20 0.33
TSHR P16473 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
PIK3CA P42336 1/20 0.32
KAT6A Q92794 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803441 0.82 ACHE (0.50) ACHECD44ALDH1A1GABRA1GABRB2
SCHEMBL24105727 0.82 ACHE (0.50) ACHECD44ALDH1A1GABRA1GABRB2
SCHEMBL22989913 0.80 ACHE (0.48) ACHEALDH1A1GABRA1GABRB2CYP1A2
SCHEMBL4553968 0.77 ACHE (0.50) ACHEALDH1A1CYP1A2CYP2A6TRPA1
SCHEMBL22024000 0.77 ACHE (0.44) ACHEKIF11ALDH1A1GABRA1GABRB2
SCHEMBL17552748 0.75 ACHE (0.43) ACHEKIF11ALDH1A1GABRA1GABRB2
SCHEMBL24554609 0.74 ACHE (0.38) ACHEKIF11CA1CA2CA7
SCHEMBL20250030 0.72 KAT6A (0.41) ACHEALDH1A1KAT6A
SCHEMBL1639725 0.72
SCHEMBL279180 0.71 CYP3A4 (0.39) ACHECD44CYP3A4TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed