Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 8/20 | 0.49 |
| ▸ | MC5R | P33032 | 7/20 | 0.49 |
| ▸ | MC3R | P41968 | 7/20 | 0.49 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22722172 | 0.96 | ADRA2C (0.63) | ADRA2CMC4RMC5RMC3RLIMK2 | |
| SCHEMBL9065743 | 0.86 | ADRA2C (0.58) | ADRA2CMC4RMC5RMC3RLIMK2 | |
| SCHEMBL14327337 | 0.85 | ADRA2C (0.56) | ADRA2CLIMK2HPGDGAAALDH1A1 | |
| SCHEMBL4629493 | 0.84 | ADRA2C (0.41) | ADRA2CMC4RMC5RMC3RLIMK2 | |
| SCHEMBL14054689 | 0.82 | HPGD (0.43) | ADRA2CMC4RMC5RMC3RHPGD | |
| SCHEMBL8374583 | 0.82 | HPGD (0.62) | HPGDGAAALDH1A1HDAC1HDAC6 | |
| SCHEMBL4630075 | 0.82 | ADRA2C (0.42) | ADRA2CMC4RMC5RMC3RLIMK2 | |
| SCHEMBL8378738 | 0.82 | HPGD (0.62) | HPGDGAAALDH1A1HDAC1HDAC6 | |
| SCHEMBL10695878 | 0.82 | HPGD (0.62) | HPGDGAAALDH1A1HDAC1HDAC6 | |
| SCHEMBL18274820 | 0.82 | HPGD (0.62) | HPGDGAAALDH1A1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139461-A2 | AMINO DERIVATIVES TO PREVENT NEPHROTOXICITY AND CANCER | Recepticon Aps (DK) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008113364-A2 | AMINO DERIVATIVES TO PREVENT NEPHROTOXICITY AND CANCER | RECEPTICON APS (DK) | 2008-09-25 | — | — | WO | disclosed |