SCHEMBL9065743

SCHEMBL9065743

NCCCCCCN(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.58
MC4R P32245 3/20 0.43
MC5R P33032 3/20 0.43
MC3R P41968 3/20 0.43
F2 P00734 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
LIMK2 P53671 1/20 0.39
KIF11 P52732 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3668677 0.86 ADRA2C (0.58) ADRA2CMC4RMC5RMC3RLIMK2
SCHEMBL633271 0.85 ADRA2C (0.56) ADRA2CL3MBTL1MAPTTDP1LIMK2
SCHEMBL28820266 0.83 ALDH1A1 (0.44) ADRA2CL3MBTL1LMNAMAPT
SCHEMBL28862080 0.83 HDAC3 (0.44) ADRA2C
SCHEMBL28959039 0.83 ALDH1A1 (0.44) ADRA2CL3MBTL1LMNAMAPT
SCHEMBL15324781 0.83 HRH1 (0.44) ADRA2CLMNA
SCHEMBL28507772 0.83 HDAC3 (0.44) ADRA2C
SCHEMBL28907322 0.83 HDAC3 (0.44) ADRA2C
SCHEMBL22722172 0.82 ADRA2C (0.63) ADRA2CMC4RMC5RMC3RLIMK2
SCHEMBL11576587 0.82 HDAC6 (0.59) ADRA2CL3MBTL1LMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105482244-A Carbon nano-tube/polymer composite material and preparation method thereof CHINA PETROLEUM & CHEM CORP 2016-04-13 CN claimed
CN-104558859-A Polypropylene composition, preparation method thereof and pipe prepared from polypropylene composition CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-107841054-B Polypropylene composition, polypropylene material and application thereof 中国石油化工股份有限公司 2020-06-30 CN disclosed
CN-107841036-B Polypropylene composition, polypropylene material and application thereof 中国石油化工股份有限公司 2020-06-30 CN disclosed
CN-105566746-A Polypropylene composition and polypropylene material, as well as application thereof CHINA PETROLEUM & CHEM CORP 2016-05-11 CN disclosed
CN-105482244-A Carbon nano-tube/polymer composite material and preparation method thereof CHINA PETROLEUM & CHEM CORP 2016-04-13 CN disclosed
CN-104558821-A Polypropylene composition and polypropylene material as well as application thereof CHINA PETROLEUM & CHEMICAL 2015-04-29 CN disclosed
CN-104558859-A Polypropylene composition, preparation method thereof and pipe prepared from polypropylene composition CHINA PETROLEUM & CHEMICAL 2015-04-29 CN disclosed
EP-0705877-A1 Whisker-reinforced thermoplastic resin composition Tonen Chemical Corporation (JP) 1996-04-10 EP disclosed