Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670148 | 0.86 | KMT2A (0.35) | MAPT | |
| SCHEMBL16493948 | 0.85 | MAPT (0.31) | MAPTHTT | |
| Hydrochloric Acid SCHEMBL3665460 | 0.83 | MAPT (0.32) | MAPTHTT | |
| SCHEMBL1204332 | 0.76 | BAZ2B (0.46) | MAPT | |
| SCHEMBL1205982 | 0.74 | KDM4E (0.39) | MAPT | |
| SCHEMBL10204128 | 0.71 | RXFP1 (0.38) | — | |
| SCHEMBL9907111 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL1205708 | 0.70 | RXFP1 (0.37) | — | |
| Bromide SCHEMBL1187591 | 0.68 | MEN1 (0.32) | MAPT | |
| Trifluoroacetic Acid SCHEMBL1188369 | 0.68 | ALDH1A1 (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240487-B1 | TRIAZOLOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS | SANOFI SA (FR) | 2011-12-14 | — | — | EP | disclosed |
| EP-2240487-A1 | TRIAZOLOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS | Sanofi-Aventis (FR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009097970-A1 | TRIAZOLOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |