Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 3/20 | 0.40 |
| ▸ | FNTB | P49356 | 3/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367200 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL365934 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL371112 | 0.83 | IDO1 (0.51) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL364930 | 0.82 | MAPT (0.51) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL366810 | 0.82 | PTGS2 (0.45) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL365778 | 0.81 | EGFR (0.42) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL366875 | 0.81 | EGFR (0.42) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL365854 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL365013 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL364760 | 0.79 | KDM4E (0.63) | KDM4EALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |