Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365401 | 0.91 | MEN1 (0.42) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL365102 | 0.89 | KDM4E (0.41) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL367346 | 0.86 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL367248 | 0.85 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL367690 | 0.85 | MEN1 (0.43) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL366694 | 0.83 | MKNK1 (0.41) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL366915 | 0.79 | PSEN1 (0.37) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL366564 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL365785 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL366905 | 0.76 | KDM4E (0.37) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |