Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366830 | 0.86 | ALDH1A1 (0.35) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL366806 | 0.86 | ALDH1A1 (0.35) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL365102 | 0.80 | KDM4E (0.41) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL366906 | 0.80 | HTT (0.37) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL366694 | 0.79 | MKNK1 (0.41) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL365401 | 0.78 | MEN1 (0.42) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL366914 | 0.76 | ALDH1A1 (0.41) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL365081 | 0.75 | KDM4E (0.38) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL366831 | 0.72 | MCL1 (0.35) | MEN1KMT2AALDH1A1PSEN1PSEN2 | |
| SCHEMBL366807 | 0.71 | MCL1 (0.33) | KMT2AL3MBTL1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |