Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814914 | 0.96 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1SCN9AHSD17B10LMNA | |
| SCHEMBL154893 | 0.96 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1SCN9AHSD17B10LMNA | |
| SCHEMBL3669055 | 0.91 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1SCN9AHSD17B10LMNA | |
| SCHEMBL2221463 | 0.89 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1SCN9AHSD17B10LMNA | |
| SCHEMBL3607774 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL4949107 | 0.85 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1SCN9AHSD17B10LMNA | |
| SCHEMBL3605351 | 0.85 | MAPT (0.37) | SMN1; SMN2ALDH1A1SCN9AHSD17B10LMNA | |
| SCHEMBL12181886 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1SCN9AHSD17B10LMNA | |
| SCHEMBL2221539 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL534619 | 0.83 | HSD17B10 (0.36) | SMN1; SMN2ALDH1A1HSD17B10LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139324-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | Syngeta Participations AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |