Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 11/20 | 0.45 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221539 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2PPARAPPARGALDH1A1F2 | |
| SCHEMBL3669425 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2PPARAPPARGALDH1A1F2 | |
| SCHEMBL3613497 | 0.88 | AR (0.45) | SMN1; SMN2ALDH1A1F2GLAHPGD | |
| SCHEMBL29212190 | 0.85 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1F2GLAHPGD | |
| SCHEMBL3669055 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2PPARAPPARGALDH1A1F2 | |
| SCHEMBL535361 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2PPARAPPARGALDH1A1F2 | |
| SCHEMBL3621503 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2PPARAPPARGALDH1A1F2 | |
| SCHEMBL29814914 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1F2GLAHPGD | |
| SCHEMBL154893 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1F2GLAHPGD | |
| SCHEMBL3615306 | 0.82 | ALDH1A1 (0.44) | PPARAPPARGALDH1A1F2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| EP-2139324-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | Syngeta Participations AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | SMN1; SMN2 3466/4885PPARA 3666/4885PPARG 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.