SCHEMBL3669571

SCHEMBL3669571

COC(=O)OC1CC=CCCC1OC(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
ALDH1A1 P00352 5/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
GSR P00390 1/20 0.33
MEN1 O00255 1/20 0.33
ALOX15 P16050 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
ESR2 Q92731 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3669964 0.94 GSR (0.36) SMN1; SMN2LMNATP53TSHRALDH1A1
SCHEMBL3669966 0.94 GSR (0.36) SMN1; SMN2LMNATP53TSHRALDH1A1
SCHEMBL3674072 0.91 LMNA (0.34) SMN1; SMN2LMNATP53TSHRALDH1A1
SCHEMBL3674073 0.91 LMNA (0.34) SMN1; SMN2LMNATP53TSHRALDH1A1
SCHEMBL3677054 0.83 NPC1 (0.33) SMN1; SMN2LMNATP53TSHRMAPT
SCHEMBL3677056 0.83 NPC1 (0.33) SMN1; SMN2LMNATP53TSHRMAPT
SCHEMBL5430000 0.81 SMN1; SMN2 (0.40) SMN1; SMN2LMNATP53TSHRALDH1A1
SCHEMBL3675769 0.80 CHRM2 (0.40) SMN1; SMN2LMNATP53TSHRALDH1A1
SCHEMBL9569883 0.78 MAPT (0.38) MAPTGSR
SCHEMBL3682781 0.78 EPHX1 (0.37) SMN1; SMN2LMNATP53TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723423-B2 Gas-barrier resin composition CRYOVAC, INC. (US) 2010-05-25 US disclosed
EP-1746131-B1 Gas-barrier resin composition CRYOVAC INC (US) 2009-01-21 EP disclosed
US-7285598-B2 Polymer and process for producing the same KURARAY CO., LTD. (JP) 2007-10-23 US disclosed
US-20070093599-A1 Gas-barrier resin composition CRYOVAC, INC. (US) 2007-04-26 US disclosed
US-20070021556-A1 Gas-barrier resin composition KURARAY CO. LTD. (JP) 2007-01-25 US disclosed
EP-1746131-A2 Gas-barrier resin composition Cryovac, Inc. (US) 2007-01-24 EP disclosed
US-20060149009-A1 Produced by ring-opening, in the presence of a metal alkylidene complex comprising a ligand with an imidazolidine structure, a cyclic olefin comprising at least one cyclic olefin further comprising a hydroxy group or a functional group that can be converted into a hydroxy group, and hydrogenating KURARAY CO., LTD. (JP) 2006-07-06 US disclosed
EP-1598384-A1 NOVEL POLYMER AND PROCESS FOR PRODUCING THE SAME KURARAY CO., LTD. (JP) 2005-11-23 EP disclosed