SCHEMBL3669964

SCHEMBL3669964

COC(=O)OC1CC/C=C\CCC1OC(=O)OC

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 1/20 0.32
SERPINE1 P05121 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3669966 1.00 GSR (0.36) GSRMAPTRAB9ANPC1LMNA
SCHEMBL3669571 0.94 SMN1; SMN2 (0.40) GSRMAPTRAB9ANPC1LMNA
SCHEMBL3677056 0.88 NPC1 (0.33) GSRMAPTRAB9ANPC1LMNA
SCHEMBL3677054 0.88 NPC1 (0.33) GSRMAPTRAB9ANPC1LMNA
SCHEMBL3674072 0.85 LMNA (0.34) LMNATP53TSHRSMN1; SMN2ALDH1A1
SCHEMBL3674073 0.85 LMNA (0.34) LMNATP53TSHRSMN1; SMN2ALDH1A1
SCHEMBL9569883 0.83 MAPT (0.38) GSRMAPT
SCHEMBL3682781 0.83 EPHX1 (0.37) MAPTRAB9ANPC1LMNATP53
SCHEMBL1080565 0.79 SERPINE1 (0.38) MAPTTSHRSMN1; SMN2ALDH1A1SERPINE1
SCHEMBL9216168 0.79 CHRM2 (0.36) TSHRALDH1A1SERPINE1CYP1A2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723423-B2 Gas-barrier resin composition CRYOVAC, INC. (US) 2010-05-25 US disclosed
EP-1746131-B1 Gas-barrier resin composition CRYOVAC INC (US) 2009-01-21 EP disclosed
US-7285598-B2 Polymer and process for producing the same KURARAY CO., LTD. (JP) 2007-10-23 US disclosed
US-20070093599-A1 Gas-barrier resin composition CRYOVAC, INC. (US) 2007-04-26 US disclosed
US-20070021556-A1 Gas-barrier resin composition KURARAY CO. LTD. (JP) 2007-01-25 US disclosed
EP-1746131-A2 Gas-barrier resin composition Cryovac, Inc. (US) 2007-01-24 EP disclosed
US-20060149009-A1 Produced by ring-opening, in the presence of a metal alkylidene complex comprising a ligand with an imidazolidine structure, a cyclic olefin comprising at least one cyclic olefin further comprising a hydroxy group or a functional group that can be converted into a hydroxy group, and hydrogenating KURARAY CO., LTD. (JP) 2006-07-06 US disclosed
EP-1598384-A1 NOVEL POLYMER AND PROCESS FOR PRODUCING THE SAME KURARAY CO., LTD. (JP) 2005-11-23 EP disclosed
US-6559241-B2 Process for producing a hydrogenated polymer KURARAY CO., LTD. (JP) 2003-05-06 US disclosed
US-20020137854-A1 Process for producing a hydrogenated polymer KURARAY CO. LTD. (JP) 2002-09-26 US disclosed
EP-1241189-A1 Process for producing a hydrogenated polymer KURARAY CO., LTD. (JP) 2002-09-18 EP disclosed