Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.72 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | APOBEC3B | Q9UH17 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671390 | 0.88 | CSNK2A2 (0.65) | DGAT1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3668829 | 0.85 | DGAT1 (0.74) | DGAT1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL601944 | 0.84 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL3671454 | 0.82 | DGAT1 (0.69) | DGAT1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL3666190 | 0.82 | DGAT1 (0.57) | DGAT1KDM4EALDH1A1SMN1; SMN2CSNK2A2 | |
| SCHEMBL3669152 | 0.82 | DGAT1 (0.57) | DGAT1KDM4EALDH1A1SMN1; SMN2CSNK2A2 | |
| SCHEMBL3668679 | 0.79 | DGAT1 (0.71) | DGAT1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL3672702 | 0.79 | DGAT1 (0.59) | DGAT1KDM4EALDH1A1SMN1; SMN2CSNK2A2 | |
| SCHEMBL13357696 | 0.78 | KDM4E (0.78) | DGAT1APOBEC3GAPOBEC3AAPOBEC3BCYP1A2 | |
| SCHEMBL18762150 | 0.78 | BLM (0.70) | DGAT1APOBEC3GAPOBEC3AAPOBEC3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391611-A1 | THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-07 | — | — | EP | claimed |
| WO-2010086551-A1 | THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-08-05 | — | — | WO | claimed |
| EP-2391611-A1 | THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010086551-A1 | THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-08-05 | — | — | WO | disclosed |