Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 9/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053114 | 0.94 | NPSR1 (0.40) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL4622471 | 0.93 | NPSR1 (0.39) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL28255942 | 0.80 | CYP2C19 (0.45) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL1009636 | 0.76 | CYP2C19 (0.40) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL4554424 | 0.75 | CYP2C19 (0.41) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL13009913 | 0.75 | CYP2C19 (0.41) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL5352623 | 0.74 | EED (0.42) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL10046851 | 0.74 | EED (0.42) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL12083378 | 0.74 | CYP2C19 (0.39) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL8980509 | 0.74 | CYP2C19 (0.51) | CYP2C19TSHRCYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238144-A1 | COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP | UCB Pharma, S.A. (BE) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009092764-A1 | COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP | UCB PHARMA, S.A. (BE) | 2009-07-30 | — | — | WO | disclosed |
| EP-2049548-A1 | FUSED OXAZOLES & THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012010-A1 | FUSED OXAZOLES & THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS | UCB PHARMA, S.A. (BE) | 2008-01-31 | — | — | WO | disclosed |