SCHEMBL3670401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3674260	0.98	SIGMAR1 (0.47)	HRH3SIGMAR1ALDH1A1POLBMAPT
	SCHEMBL791907	0.82	CHRM2 (0.51)	HRH3SIGMAR1ALDH1A1POLBMAPT
	SCHEMBL3673101	0.81	GLA (0.46)	ALDH1A1MAPT
	SCHEMBL25980412	0.80	HRH3 (0.45)	HRH3SIGMAR1
	SCHEMBL7006254	0.80	CHRM2 (0.53)	HRH3SIGMAR1ALDH1A1POLBMAPT
	Hydrochloric Acid SCHEMBL2112394	0.79	HRH3 (0.48)	HRH3SIGMAR1ALDH1A1POLBMAPT
	SCHEMBL14175033	0.78	KMT2A (0.39)	HRH3SIGMAR1ALDH1A1POLBMAPT
	SCHEMBL7003764	0.78	HRH3 (0.46)	HRH3SIGMAR1ALDH1A1POLBMAPT
	SCHEMBL22861409	0.78	SIGMAR1 (0.50)	HRH3SIGMAR1ALDH1A1POLBMAPT
	SCHEMBL26275998	0.78	HRH3 (0.49)	HRH3SIGMAR1ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.