SCHEMBL3674260

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3670401	0.98	HRH3 (0.48)	SIGMAR1HRH3ALDH1A1POLBMAPT
	SCHEMBL3673101	0.83	GLA (0.46)	ALDH1A1MAPT
	SCHEMBL25980412	0.82	HRH3 (0.45)	SIGMAR1HRH3CHRM2CHRM4CHRM5
	SCHEMBL7006254	0.82	CHRM2 (0.53)	SIGMAR1HRH3ALDH1A1POLBMAPT
	SCHEMBL791907	0.80	CHRM2 (0.51)	SIGMAR1HRH3ALDH1A1POLBMAPT
	SCHEMBL14175033	0.79	KMT2A (0.39)	SIGMAR1HRH3ALDH1A1POLBMAPT
	SCHEMBL7004839	0.78	SIGMAR1 (0.52)	SIGMAR1HRH3
	SCHEMBL12304468	0.77	HRH3 (0.47)	SIGMAR1HRH3
	Hydrochloric Acid SCHEMBL2112394	0.77	HRH3 (0.48)	SIGMAR1HRH3ALDH1A1POLBMAPT
	SCHEMBL14207598	0.77	SIGMAR1 (0.44)	SIGMAR1HRH3ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.