SCHEMBL3670792

SCHEMBL3670792

COCc1ccc(C(=O)C(C)(C)O)cc1COC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.36
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
POLB P06746 2/20 0.35
PRKCE Q02156 2/20 0.35
TDP1 Q9NUW8 2/20 0.33
ACE2 Q9BYF1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PKM P14618 1/20 0.33
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
MLYCD O95822 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
ACHE P22303 1/20 0.33
PRKCG P05129 1/20 0.33
PRKCA P17252 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3673889 0.95 ALDH1A1 (0.34) MEN1ALDH1A1KMT2AMAPTGAA
SCHEMBL3674798 0.95 ALDH1A1 (0.34) MEN1ALDH1A1KMT2AMAPTGAA
SCHEMBL3671819 0.95 ALDH1A1 (0.34) MEN1ALDH1A1KMT2AMAPTGAA
SCHEMBL3667698 0.92 ACE2 (0.40) MEN1ALDH1A1KMT2AMAPTGAA
SCHEMBL3673304 0.92 ACE2 (0.40) MEN1ALDH1A1KMT2AMAPTGAA
SCHEMBL3675044 0.90 ALDH1A1 (0.47) MEN1ALDH1A1KMT2AMAPTGAA
SCHEMBL3679218 0.88 ALDH1A1 (0.46) MEN1ALDH1A1KMT2AMAPTGAA
SCHEMBL3675000 0.85 CA12 (0.35) ACE2MLYCDRAB9AACHE
SCHEMBL3672629 0.81 ACE2 (0.39) ACE2PKM
SCHEMBL3672690 0.81 KMT2A (0.44) ALDH1A1KMT2AMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642296-B2 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-05 US disclosed
US-7642296-B2 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-05 US disclosed
US-7642296-B2 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-05 US disclosed
US-20070240609-A1 Photoinitiators IGM GROUP B.V. (NL) 2007-10-18 US disclosed
US-20070240609-A1 Photoinitiators IGM GROUP B.V. (NL) 2007-10-18 US disclosed
US-20070240609-A1 Photoinitiators IGM GROUP B.V. (NL) 2007-10-18 US disclosed
EP-1763499-B1 NEW PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2007-09-26 EP disclosed
EP-1763499-B1 NEW PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2007-09-26 EP disclosed
EP-1763499-A1 NEW PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-03-21 EP disclosed
WO-2005100292-A1 NEW PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-10-27 WO disclosed