Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYBB | P04839 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671501 | 0.97 | ACE2 (0.40) | ACE2PKMCYBBMAPK1EPHX2 | |
| SCHEMBL3677422 | 0.97 | ACE2 (0.40) | ACE2PKMCYBBMAPK1S1PR1 | |
| SCHEMBL3671847 | 0.89 | ACE2 (0.45) | ACE2PKMCYBBEPHX2 | |
| SCHEMBL3667698 | 0.87 | ACE2 (0.40) | ACE2PKMCYBBEPHX2 | |
| SCHEMBL3673889 | 0.87 | ALDH1A1 (0.34) | ACE2PKMMAPK1S1PR1S1PR3 | |
| SCHEMBL3671819 | 0.87 | ALDH1A1 (0.34) | ACE2PKMMAPK1S1PR1S1PR3 | |
| SCHEMBL3674798 | 0.87 | ALDH1A1 (0.34) | ACE2PKMMAPK1S1PR1S1PR3 | |
| SCHEMBL3673304 | 0.87 | ACE2 (0.40) | ACE2PKMCYBB | |
| SCHEMBL3675000 | 0.86 | CA12 (0.35) | ACE2MAPK1S1PR1S1PR3TSHR | |
| SCHEMBL3668232 | 0.83 | ACE2 (0.43) | ACE2PKMEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |