SCHEMBL3671111

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4793316	0.72	ALDH1A1 (0.40)	ALDH1A1HTTTDP1POLBNPC1
	SCHEMBL7792276	0.72	SMPD3 (0.51)	ALDH1A1HTTKDM4ETDP1POLB
	SCHEMBL29684098	0.70	TDP1 (0.48)	ALDH1A1HTTKDM4ETDP1POLB
	SCHEMBL5761567	0.70	TDP1 (0.39)	ALDH1A1HTTKDM4ETDP1POLB
	SCHEMBL5234266	0.68	MAP4K4 (0.46)	ALDH1A1HTTKDM4EGLANCOA1
	SCHEMBL2032616	0.68	MAP4K4 (0.46)	ALDH1A1HTTKDM4ENPC1RAB9A
	SCHEMBL19942301	0.68	MAP4K4 (0.46)	ALDH1A1HTTKDM4EGLANCOA1
	SCHEMBL398829	0.68	MAP4K4 (0.60)	ALDH1A1HTTKDM4ENPC1RAB9A
	SCHEMBL2661228	0.68	ALDH1A1 (0.49)	ALDH1A1HTTKDM4EGLANCOA1
	SCHEMBL10289637	0.68	HTT (0.51)	ALDH1A1HTTKDM4EGLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.