SCHEMBL3671209

SCHEMBL3671209

N#CC[C](C#N)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29187297 0.69 KDM4E (0.43)
SCHEMBL11513625 0.65
SCHEMBL11405904 0.65
SCHEMBL1996348 0.65
SCHEMBL28654966 0.65
SCHEMBL11366819 0.62 KDM4E (0.50)
SCHEMBL503976 0.61 MCL1 (0.40)
SCHEMBL11895365 0.61 MCL1 (0.41)
SCHEMBL2473688 0.61 MCL1 (0.41)
SCHEMBL57647 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308740-A1 Process for the preparation of 2,4-dichloro-5-dichloromethyl thiazole BAYER AG (DE) 1989-03-29 EP claimed
US-20230229077-A1 PHOTOACID GENERATOR FOR CHEMICALLY AMPLIFIED PHOTORESISTS FOR DEEP ULTRAVIOLET AND EXTREME ULTRAVIOLET LITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION 2023-07-20 US disclosed
EP-2099845-B1 MULTI-FUNCTIONAL POLYALKYLENE OXIDES, HYDROGELS AND TISSUE ADHESIVES ACTAMAX SURGICAL MAT LLC (US) 2020-12-23 EP disclosed
US-9466431-B2 Ionic compound and process for production thereof, and electrolytic solution and electrical storage device each utilizing the ionic compound NIPPON SHOKUBAI CO., LTD. (JP) 2016-10-11 US disclosed
CN-103370827-B Ionic compound, method for producing same, and electrolyte solution and electricity storage device using same NIPPON SHOKUBAI CO.,LTD. (JP) 2016-02-17 CN disclosed
EP-2667445-A1 IONIC COMPOUND AND PROCESS FOR PRODUCTION THEREOF, AND ELECTROLYTIC SOLUTION AND ELECTRICAL STORAGE DEVICE EACH UTILIZING THE IONIC COMPOUND Nippon Shokubai Co., Ltd. (JP) 2013-11-27 EP disclosed
US-20130295449-A1 IONIC COMPOUND AND PROCESS FOR PRODUCTION THEREOF, AND ELECTROLYTIC SOLUTION AND ELECTRICAL STORAGE DEVICE EACH UTILIZING THE IONIC COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 2013-11-07 US disclosed
US-8282959-B2 Branched end reactants and polymeric hydrogel tissue adhesives therefrom ACTAMAX SURGICAL MATERIALS, LLC (US) 2012-10-09 US disclosed
US-20100086678-A1 BRANCHED END REACTANTS AND POLYMERIC HYDROGEL TISSUE ADHESIVES THEREFROM E.I.DUPONT DE NEMOURS AND COMPANY (DE) 2010-04-08 US disclosed
EP-2099845-A2 BRANCHED END REACTANTS AND POLYMERIC HYDROGEL TISSUE ADHESIVES THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-16 EP disclosed
WO-2008066787-A2 MULTI-FUNCTIONAL POLYALKYLENE OXIDES, HYDROGELS AND TISSUE ADHESIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-06-05 WO disclosed
EP-0339217-B1 Specific peptide bond cleavage by organic tertiary phosphines with nucleophilic side chains CARTER WALLACE (US) 1994-09-21 EP disclosed
US-4956467-A CLEAVAGE OF PROTEINS AND SEQUENCE DETERMINATION AMERICAN CYANAMID COMPANY (US) 1990-09-11 US disclosed
EP-0339217-A2 Specific peptide bond cleavage by organic tertiary phosphines with nucleophilic side chains CARTER-WALLACE, INC. (US) 1989-11-02 EP disclosed
US-4684751-A HYDRATION OF NITRILES AND ALKENES, PHASE TRANSFER AGENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1987-08-04 US disclosed