Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 1.00 |
| ▸ | HPGD | P15428 | 7/20 | 1.00 |
| ▸ | GLA | P06280 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 10/20 | 0.73 |
| ▸ | NPC1 | O15118 | 7/20 | 0.73 |
| ▸ | GAA | P10253 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560123 | 0.88 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL5305847 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL17750396 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL17750395 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL1692157 | 0.85 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL17626882 | 0.85 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL1494735 | 0.85 | RAB9A (1.00) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL8010439 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL971743 | 0.85 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL9298339 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10930853-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| CN-110590774-B | Trifluoromethyl imidazole condensed ring compound and preparation method thereof | 河南中医药大学 | 2020-09-08 | — | — | CN | disclosed |
| CN-110590774-A | Trifluoromethyl imidazole condensed ring compound and preparation method thereof | 河南中医药大学 | 2019-12-20 | — | — | CN | disclosed |
| US-9801961-B2 | 2-phenylimidazo[1,2-a]pyrimidines as imaging agents | HOFFMANN-LA ROCHE INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170155048-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-01 | — | — | US | disclosed |
| US-9012042-B2 | Condensed-cyclic compound, organic light-emitting device comprising the same, and flat panel display apparatus | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-04-21 | — | — | US | disclosed |
| US-20120286246-A1 | CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME, AND FLAT PANEL DISPLAY APPARATUS | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2012-11-15 | — | — | US | disclosed |
| EP-2237788-A2 | AEROSOLIZED NITRITE AND NITRIC OXIDE - DONATING COMPOUNDS AND USES THEREOF | Aires Pharmaceuticals, Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009086470-A2 | AEROSOLIZED NITRITE AND NITRIC OXIDE - DONATING COMPOUNDS AND USES THEREOF | AIRES PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| EP-1660500-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | S A L V A T LAB SA (ES) | 2007-12-12 | — | — | EP | disclosed |
| US-4636502-A | Methods of producing a positive inotropic effect or vasodilation by administration of 2-phenyl imidazo pyrimidines and pyrazines | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4578387-A | VASODILATION; DERIVATIVES OF 2-PHENYL-5,6,7,8-TETRAHYDROIMADAZO/1,2-A/PYRAZINE | ELI LILLY AND COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| EP-0154494-A2 | Phenylimidazole inotropic agents | ELI LILLY AND COMPANY (US) | 1985-09-11 | — | — | EP | disclosed |
| US-4537889-A | PHENYL SUBSTITUTED IMIDAZO COMPOUNDS | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0113236-A1 | Substituted imidazopyrimidines-pyrazines, and -triazines | ELI LILLY AND COMPANY (US) | 1984-07-11 | — | — | EP | disclosed |
| US-4419289-A | YELLOW COLOR FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ESTERS | EASTMAN KODAK COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| US-4396547-A | INDOLE, THIADIAZOLE AND MONOAZO DYES | EASTMAN KODAK COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4354970-A | YELLOW TEXTILE DYE | EASTMAN KODAK COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
| US-4255573-A | Imidazoindole derivatives and pharmaceutical compositions comprising imidazoindole derivatives | ADHIKARY PARIMAL K | 1981-03-10 | — | — | US | disclosed |
| US-4242513-A | CHROMOGENS; PRESSURE AND HEAT SENSITIVE MARKING | APPLETON PAPERS INC. (US) | 1980-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120286246-A1 | CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME, AND FLAT PANEL DISPLAY APPARATUS | OR10J3, AR, ARL1 | ALDH1A1 578/4885KDM4E 2875/4885HPGD 4476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.