Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731304 | 0.92 | CTSA (0.39) | CTSAS1PR1FFAR1PTGDR2TRPM8 | |
| SCHEMBL1951055 | 0.88 | PTGDR2 (0.51) | CTSAFFAR1PTGDR2LTB4R2 | |
| SCHEMBL3666383 | 0.85 | S1PR1 (0.43) | S1PR1PTGDR2CYP2D6CACNA1BKDM4E | |
| SCHEMBL3667571 | 0.82 | MGLL (0.42) | S1PR1PTGDR2CACNA1BKDM4ETHRA | |
| SCHEMBL3665828 | 0.82 | FSHR (0.38) | S1PR1PTGDR2PPARGPPARACYP2D6 | |
| SCHEMBL3671421 | 0.81 | GPBAR1 (0.41) | CTSAPTGDR2TRPM8CYP2D6CACNA1B | |
| SCHEMBL3666210 | 0.80 | FSHR (0.40) | S1PR1PTGDR2PPARGPPARACYP2D6 | |
| SCHEMBL3671417 | 0.80 | GPBAR1 (0.41) | CTSAPTGDR2TRPM8 | |
| SCHEMBL3670884 | 0.79 | PTGDR2 (0.44) | S1PR1PTGDR2KDM4ETHRATHRB | |
| SCHEMBL3666381 | 0.77 | S1PR1 (0.43) | S1PR1PTGDR2CYP2D6CACNA1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |