Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673130 | 0.94 | CYP2C9 (0.49) | CYP2C9ALOX15HSD17B10CNR2CNR1 | |
| SCHEMBL3676596 | 0.87 | CYP2C9 (0.43) | CYP2C9ALOX15HSD17B10CNR2CNR1 | |
| SCHEMBL3672690 | 0.84 | KMT2A (0.44) | CYP2C9ALOX15HSD17B10CNR2CNR1 | |
| SCHEMBL3671847 | 0.79 | ACE2 (0.45) | — | |
| SCHEMBL3674751 | 0.79 | HRH3 (0.59) | HRH3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14700252 | 0.77 | ABL1 (0.53) | CYP2C9HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL3668232 | 0.76 | ACE2 (0.43) | ALDH1A1 | |
| SCHEMBL3676655 | 0.73 | ALDH1A1 (0.43) | ALOX15KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL3671501 | 0.73 | ACE2 (0.40) | — | |
| SCHEMBL4909115 | 0.72 | CYP2A13 (0.55) | CYP2C9ALOX15HSD17B10CYP2A13KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |