Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671847 | 0.93 | ACE2 (0.45) | ACE2PKMHSP90AA1HSP90AB1MLYCD | |
| SCHEMBL3671501 | 0.85 | ACE2 (0.40) | ACE2PKMMLYCDEPHX2ACHE | |
| SCHEMBL3676655 | 0.85 | ALDH1A1 (0.43) | ACE2PKMALDH1A1 | |
| SCHEMBL3673304 | 0.84 | ACE2 (0.40) | ACE2PKMALDH1A1 | |
| SCHEMBL3672629 | 0.83 | ACE2 (0.39) | ACE2PKMEPHX2 | |
| SCHEMBL3669475 | 0.83 | ACE2 (0.43) | ACE2PKMMLYCDEPHX2ACHE | |
| SCHEMBL3676253 | 0.83 | PKM (0.46) | ACE2PKMEPHX2HSD17B1KLF10 | |
| SCHEMBL3677422 | 0.82 | ACE2 (0.40) | ACE2PKMMLYCDEPHX2ACHE | |
| SCHEMBL3672838 | 0.81 | PKM (0.41) | ACE2PKMEPHX2KLF10 | |
| SCHEMBL3667698 | 0.81 | ACE2 (0.40) | ACE2PKMMLYCDEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |