SCHEMBL771546

SCHEMBL771546

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.61
THRB P10828 1/20 0.47
CA2 P00918 3/20 0.42
CA1 P00915 2/20 0.38
MMP1 P03956 2/20 0.38
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP13 P45452 2/20 0.38
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perflenapent SCHEMBL7648533 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
SCHEMBL984715 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
SCHEMBL3743142 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
SCHEMBL1924377 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
Perflexane SCHEMBL3671912 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
SCHEMBL1707474 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
Perflexane SCHEMBL7507426 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
SCHEMBL1779065 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
Perflexane SCHEMBL20769778 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1
Perflenapent SCHEMBL33962 1.00 LMNA (0.61) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144875-A1 COMPOSITIONS AND METHODS FOR CROSSLINKING STRUCTURAL PROTEINS ADS THERAPEUTICS LLC (US) 2026-05-28 US claimed
CN-122075746-A Microsphere composition, preparation method thereof and application thereof in preparation of contrast agent and medicine 2026-05-26 CN claimed
US-20260130896-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF OPHTHALMOLOGICAL ACTIVES ADS THERAPEUTICS LLC (US) 2026-05-14 US claimed
US-20260124305-A1 TOPICAL OPHTHALMOLOGICAL COMPOSITIONS ADS THERAPEUTICS LLC (US) 2026-05-07 US claimed
EP-4717278-A1 NANOVECTORS FOR MAGNETIC RESONANCE IMAGING Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2026-04-01 EP claimed
US-20250375539-A1 COMPOSITIONS OF DISPERSED SYSTEMS FOR BIOMEDICAL APPLICATIONS, PROCESS FOR THEIR PREPARATION AND USES THEREOF SUPERBRANCHE (FR) 2025-12-11 US claimed
US-20250345287-A1 COMPOSITION COMPRISING A MIXTURE OF AT LEAST ONE OIL AND ONE OR MORE SEMIFLUORINATED ALKANES, A USE OF THE COMPOSITION FOR TREATING A DISEASE AS WELL AS A METHOD OF PRODUCING THE COMPOSITION AND CORRESPONDING KITS FLUORON GMBH (DE) 2025-11-13 US claimed
EP-4647066-A1 A COMPOSITION COMPRISING A MIXTURE OF AT LEAST ONE OIL AND ONE OR MORE SEMIFLUORINATED ALKANES, A USE OF THE COMPOSITION FOR TREATING A DISEASE AS WELL AS A METHOD OF PRODUCING THE COMPOSITION AND CORRESPONDING KITS Fluoron GmbH (DE) 2025-11-12 EP claimed
US-20250339598-A1 EXTRACORPOREAL OXYGENATION DEVICE BOUNDLESS SCIENCE INCORPORATED (US) 2025-11-06 US claimed
EP-4637775-A1 COMPOSITIONS AND METHODS FOR CROSSLINKING STRUCTURAL PROTEINS ADS Therapeutics LLC (US) 2025-10-29 EP claimed
EP-1870398-B1 One-pot catalytic process for the synthesis of isocyanates REPSOL YPF SA (ES) 2008-12-17 EP claimed
US-7423171-B2 One-step catalytic process for the synthesis of isocyanates REPSOL YPF, S.A. (ES) 2008-09-09 US claimed
EP-1933393-A1 Method of manufacturing a substrate for an electronic device Samsung SDI Co., Ltd. (KR) 2008-06-18 EP claimed
EP-1870398-A1 One-pot catalytic process for the synthesis of isocyanates REPSOL YPF S.A. (ES) 2007-12-26 EP claimed
US-20070293696-A1 ONE-STEP CATALYTIC PROCESS FOR THE SYNTHESIS OF ISOCYANATES REPSOL-YPF,S.A. (ES) 2007-12-20 US claimed
US-20050176140-A1 Method and apparatus for cell culture using a two liquid phase bioreactor BENEDICT DANIEL J (US) 2005-08-11 US claimed
EP-0612240-A4 METHOD FOR EXTENDING THE VASCULAR DWELL-TIME OF PARTICULATE THERAPEUTIC AND PARTICULATE DIAGNOSTIC AGENTS. LONG DAVID M JR (US) 1995-05-17 EP claimed
EP-0612240-A1 METHOD FOR EXTENDING THE VASCULAR DWELL-TIME OF PARTICULATE THERAPEUTIC AND PARTICULATE DIAGNOSTIC AGENTS Long, David M., Jr. (US) 1994-08-31 EP claimed
US-5264220-A Blood substitute LONG DAVID M JR (US) 1993-11-23 US claimed
WO-1993009762-A2 METHOD FOR EXTENDING THE VASCULAR DWELL-TIME OF PARTICULATE THERAPEUTIC AND PARTICULATE DIAGNOSTIC AGENTS LONG DAVID M JR (US) 1993-05-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375539-A1 COMPOSITIONS OF DISPERSED SYSTEMS FOR BIOMEDICAL APPLICATIONS, PROCESS FOR THEIR PREPARATION AND USES THEREOF TLR3, MSR1, DCLRE1B LMNA 2783/4885THRB 4078/4885CA2 2156/4885
US-20070293696-A1 ONE-STEP CATALYTIC PROCESS FOR THE SYNTHESIS OF ISOCYANATES ADH1C, IDH2, CYP4F2 LMNA 1814/4885THRB 3850/4885CA2 90/4885
US-20260124305-A1 TOPICAL OPHTHALMOLOGICAL COMPOSITIONS CHRM5, FFAR3, CHRM2 LMNA 2553/4885THRB 53/4885CA2 2160/4885
US-20260130896-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF OPHTHALMOLOGICAL ACTIVES CHRM5, CHRM3, CHRM2 LMNA 2401/4885THRB 223/4885CA2 1000/4885
US-20260144875-A1 COMPOSITIONS AND METHODS FOR CROSSLINKING STRUCTURAL PROTEINS STRA6, RBP4, F12 LMNA 3320/4885THRB 305/4885CA2 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.