Florasulam

Florasulam

SCHEMBL3671917

CCCCCC(C)OC(=O)COc1ccc(Cl)c2cccnc12.COc1ncc(F)c2nc(S(=O)(=O)Nc3c(F)cccc3F)nn12

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
PKM P14618 1/20 0.36
KDM4E B2RXH2 5/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GAA P10253 1/20 0.31
POLB P06746 4/20 0.31
KMT2A Q03164 2/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX12 P18054 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
RAB9A P51151 1/20 0.31
MEN1 O00255 1/20 0.30
GLA P06280 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flufenacet SCHEMBL6061596 0.86 L3MBTL1 (0.30) L3MBTL1
Florasulam SCHEMBL3263322 0.80
SCHEMBL29452812 0.77 MAPT (0.61) MAPTPKMKDM4EL3MBTL1ALDH1A1
SCHEMBL9828522 0.77 MAPT (0.61) MAPTPKMKDM4EL3MBTL1ALDH1A1
SCHEMBL9828807 0.77 MAPT (0.61) MAPTPKMKDM4EL3MBTL1ALDH1A1
SCHEMBL29372446 0.77 MAPT (0.61) MAPTPKMKDM4EL3MBTL1ALDH1A1
SCHEMBL96159 0.77 MAPT (0.61) MAPTPKMKDM4EL3MBTL1ALDH1A1
Water SCHEMBL1095558 0.76 MAPT (0.60) MAPTPKMKDM4EL3MBTL1ALDH1A1
SCHEMBL9830914 0.74 PKM (0.57) MAPTPKMKDM4EL3MBTL1ALDH1A1
Florasulam SCHEMBL116614 0.72 GAA (0.39) GAAKMT2ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2232997-A1 Synergistically active herbicidal agents that are compatible with cultivated plants and contain herbicides from the group of benzoylpyrazoles Bayer CropScience AG (DE) 2010-09-29 EP disclosed
EP-2096913-A1 SYNERGISTICALLY ACTIVE HERBICIDAL AGENTS THAT ARE COMPATIBLE WITH CULTIVATED PLANTS AND CONTAIN HERBICIDES FROM THE GROUP OF BENZOYLPYRAZOLES Bayer CropScience AG (DE) 2009-09-09 EP disclosed
WO-2008064781-A1 SYNERGISTICALLY ACTIVE HERBICIDAL AGENTS THAT ARE COMPATIBLE WITH CULTIVATED PLANTS AND CONTAIN HERBICIDES FROM THE GROUP OF BENZOYLPYRAZOLES BAYER CROPSCIENCE AG (DE) 2008-06-05 WO disclosed