⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16085342 | 0.81 | — | — | |
| SCHEMBL3197403 | 0.78 | — | — | |
| SCHEMBL8068062 | 0.74 | ADH1B (0.71) | — | |
| SCHEMBL10892758 | 0.74 | HDAC3 (0.43) | — | |
| SCHEMBL499577 | 0.73 | — | — | |
| SCHEMBL5860428 | 0.72 | — | — | |
| SCHEMBL11467304 | 0.72 | ADH1B (0.56) | — | |
| SCHEMBL8764004 | 0.72 | ADH1B (0.72) | — | |
| SCHEMBL11322360 | 0.72 | ADH1B (0.72) | — | |
| SCHEMBL8763225 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | claimed |
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-12-16 | — | — | US | claimed |
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | claimed |
| WO-2009065406-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2009-05-28 | — | — | WO | claimed |
| US-20220323591-A1 | HEPARIN NANO DRUG CARRIER SYSTEM LOADED WITH AMINO ANTI-TUMOR DRUG AND PREPARATION METHOD THEREOF | NANJING KING-FRIEND BIOCHEMICAL PHARMACEUTICAL CO., LTD. (CN) | 2022-10-13 | — | — | US | disclosed |
| US-11160871-B2 | SSTR-targeted conjugates and particles and formulations thereof | TARVEDA THERAPEUTICS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-10624967-B2 | Targeted conjugates and particles and formulations thereof | TARVEDA THERAPEUTICS, INC. (US) | 2020-04-21 | — | — | US | disclosed |
| US-20180221499-A1 | SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2018-08-09 | — | — | US | disclosed |
| WO-2018042367-A2 | COMPOUNDS, COMPOSITONS AND METHODS RELATED TO ANTIMICROBIAL APPLICATIONS | VYOME BIOSCIENCES PVT. LTD. (IN) | 2018-03-08 | — | — | WO | disclosed |
| US-20170135970-A1 | N-ACETYLCYSTEINE AMIDE (NAC AMIDE) IN THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS | GOLDSTEIN GLENN A (US) | 2017-05-18 | — | — | US | disclosed |
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | disclosed |
| US-9452392-B2 | Gas separation composite membrane and method of producing the same, and gas separating module, gas separation apparatus and gas separation method using the same | FUJIFILM CORPORATION (JP) | 2016-09-27 | — | — | US | disclosed |
| US-RE30560-E | VINCRISTINE SUBSTITUTES; ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
| US-RE30561-E | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
| US-4256767-A | Phenoxy alkylamides | SOCIETE D'ETUDES DE PRODUITS CHIMIQUES (FR) | 1981-03-17 | — | — | US | disclosed |
| US-4203898-A | ANTICARCINOGENIC | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4199504-A | ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | ELI LILLY AND COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| EP-0005620-A1 | Bridged catharanthus alkaloid dimers, their preparation and formulations containing them | ELI LILLY AND COMPANY (US) | 1979-11-28 | — | — | EP | disclosed |
| US-4160767-A | 3-SPIRO-5\"-OXAZOLIDINE-2\",4\"-DIONES, ANTITUMOR AGENTS, 3-CARBAMATES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4096148-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1978-06-20 | — | — | US | disclosed |