Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.69 |
| ▸ | TK2 | O00142 | 5/20 | 0.63 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.60 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.59 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.59 |
| ▸ | TK1 | P04183 | 1/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286250 | 1.00 | PYGM (0.69) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL16808996 | 1.00 | PYGM (0.69) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL2577325 | 1.00 | PYGM (0.69) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL1286252 | 1.00 | PYGM (0.69) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL3385371 | 1.00 | PYGM (0.69) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL1272640 | 0.91 | TK2 (0.65) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL2583312 | 0.91 | TK2 (0.65) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL3416516 | 0.91 | TK2 (0.65) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL1272642 | 0.91 | TK2 (0.65) | PYGMTK2DNPH1SLC28A1SLC28A2 | |
| SCHEMBL14929135 | 0.91 | DNPH1 (0.71) | PYGMTK2DNPH1SLC28A1SLC28A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242516-A1 | METHODS AND COMPOSITIONS FOR DETECTION OF BACTERIA AND TREATMENT OF DISEASES AND DISORDERS | Genelux Corporation (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009126189-A1 | METHODS AND COMPOSITIONS FOR DETECTION OF BACTERIA AND TREATMENT OF DISEASES AND DISORDERS | GENELUX CORPORATION (US) | 2009-10-15 | — | — | WO | disclosed |
| EP-1768704-A2 | IMAGING INFECTION WITH COMPOUNDS THAT BIND TO THYMIDINE KINASE | The Johns Hopkins University (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006002142-A2 | IMAGING INFECTION WITH COMPOUNDS THAT BIND TO THYMIDINE KINASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-01-05 | — | — | WO | disclosed |