Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CCND2 | P30279 | 2/20 | 0.32 |
| ▸ | CCND3 | P30281 | 2/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688681 | 0.82 | POLB (0.42) | CDK4CCND1CCND2CCND3POLB | |
| SCHEMBL23272041 | 0.77 | HSD17B10 (0.33) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL29947955 | 0.77 | HSD17B10 (0.33) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL30692889 | 0.73 | CA12 (0.52) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL8229991 | 0.73 | CA12 (0.52) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL28947642 | 0.71 | RECQL (0.38) | KMO | |
| SCHEMBL3672244 | 0.70 | PLK1 (0.41) | KMODAO | |
| SCHEMBL28319074 | 0.70 | CA12 (0.34) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL12862551 | 0.69 | SMN1; SMN2 (0.45) | CDK4CCND1CCND2CCND3POLB | |
| SCHEMBL11868257 | 0.69 | HDAC1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203062-A2 | ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | Bayer CropScience AG (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009039951-A2 | ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2009-04-02 | — | — | WO | disclosed |