Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868257 | 0.84 | HDAC1 (0.37) | HDAC1HDAC6HDAC8TDP1ADRB1 | |
| SCHEMBL9540156 | 0.80 | POLB (0.45) | TDP1LMNAHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL11127625 | 0.77 | ADRB1 (0.35) | CNR2KMOLMNAHPGDSMN1; SMN2 | |
| SCHEMBL29093825 | 0.77 | ALDH1A1 (0.35) | PLK1ADORA2BCNR2KMOLMNA | |
| SCHEMBL10621833 | 0.76 | KMO (0.57) | KMOLMNASMN1; SMN2 | |
| SCHEMBL4795814 | 0.76 | ALDH1A1 (0.46) | TDP1LMNAHPGDCYP1A2 | |
| SCHEMBL7569439 | 0.76 | RECQL (0.42) | KMOLMNAHPGDSMN1; SMN2ADRB1 | |
| Iodide SCHEMBL10619045 | 0.75 | KMO (0.56) | KMOLMNASMN1; SMN2 | |
| SCHEMBL29094008 | 0.75 | TLR8 (0.37) | KMOLMNAHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL10619078 | 0.75 | GSK3A (0.44) | ADORA2BLMNAHPGDSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203062-A2 | ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | Bayer CropScience AG (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009039951-A2 | ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2009-04-02 | — | — | WO | disclosed |