Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 4/20 | 0.34 |
| ▸ | PLD2 | O14939 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838186 | 0.86 | DRD2 (0.47) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL1838940 | 0.79 | OPRM1 (0.42) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL1833975 | 0.78 | OPRM1 (0.47) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL1833681 | 0.78 | OPRM1 (0.52) | BCHEACHEOPRM1OPRL1PLD1 | |
| SCHEMBL1836059 | 0.77 | OPRM1 (0.55) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL1835710 | 0.76 | OPRM1 (0.58) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL1836591 | 0.75 | PLD1 (0.51) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL1831703 | 0.75 | OPRM1 (0.47) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL3400375 | 0.75 | OPRM1 (0.47) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL3403017 | 0.75 | OPRM1 (0.50) | DRD2DRD4DRD3BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |