SCHEMBL3672316

SCHEMBL3672316

FC(F)(F)C(F)(c1ccc(I)cc1)c1ccc(I)cc1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.38
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1229916 0.78 TRPV1 (0.38) TRPV1ESR1ESR2APP
SCHEMBL3672506 0.78 ESR1 (0.56) TRPV1ESR1ESR2APP
SCHEMBL5354856 0.78 TRPV1 (0.38) TRPV1ESR1ESR2APP
SCHEMBL1616 0.77 TRPV1 (0.55) TRPV1
SCHEMBL3677277 0.77 TRPV1 (0.41) TRPV1ESR1ESR2APP
SCHEMBL25191871 0.74 TRPV1 (0.53) TRPV1
SCHEMBL10821826 0.74 APP (0.35) TRPV1APP
SCHEMBL15238196 0.74 APP (0.50) TRPV1APP
SCHEMBL2438938 0.74 APP (0.50) TRPV1APP
SCHEMBL19224 0.74 NR1H2 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
EP-1245554-B1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORP (JP) 2005-01-26 EP disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6794480-B2 POLYARYLENE-BASED COPOLYMER USEFUL AS PROTON-CONDUCTIVE MEMBRANE WHICH CAN BE USED AS ELECTRON FOR PRIMARY BATTERY, ELECTROLYTE FOR SECONDARY BATTERY, HIGH MOLECULAR SOLID ELECTROLYTE FOR FUEL CELL JSR CORPORATION (JP) 2004-09-21 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed