SCHEMBL1616

SCHEMBL1616

FC(F)(F)c1ccc(I)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.55
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
KIF11 P52732 6/20 0.48
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
ORAI1 Q96D31 1/20 0.46
ORAI2 Q96SN7 1/20 0.46
ORAI3 Q9BRQ5 1/20 0.46
TRPV6 Q9H1D0 1/20 0.46
MGLL Q99685 1/20 0.46
TAAR1 Q96RJ0 1/20 0.42
EPHX2 P34913 1/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
PLAU P00749 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28192244 0.97 TRPV1 (0.53) TRPV1ALDH1A1TSHRKIF11CES2
SCHEMBL25191871 0.97 TRPV1 (0.53) TRPV1ALDH1A1TSHRKIF11CES2
SCHEMBL5695842 0.92 TRPV1 (0.50) TRPV1ALDH1A1TSHRKIF11CES2
SCHEMBL6547427 0.92 KIF11 (0.61) TRPV1ALDH1A1TSHRKIF11
SCHEMBL20526038 0.87 TRPV1 (0.47) TRPV1ALDH1A1TSHRKIF11CES2
SCHEMBL5907707 0.87 KIF11 (0.67) TRPV1TSHRKIF11CES2CES1
SCHEMBL9987935 0.85 TRPV1 (0.46) TRPV1ALDH1A1TSHRKIF11
SCHEMBL25523869 0.85 TRPV1 (0.46) TRPV1ALDH1A1TSHRKIF11CES2
SCHEMBL9440464 0.85 SRD5A2 (0.50) TRPV1ALDH1A1KIF11TAAR1IDO1
SCHEMBL27257744 0.85 TRPV1 (0.46) TRPV1ALDH1A1TSHRKIF11CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119972144-A Method for preparing phenol or ether compound by photocatalysis 中国科学院化学研究所 2025-05-13 CN claimed
CN-116283659-B Preparation method and application of m-nitrobenzonitrile 上海忝晴化工有限公司 2025-04-25 CN claimed
CN-119346167-A Catalytic system and method for synthesizing diaryl acetylene from calcium carbide and iodo aromatic hydrocarbon 石河子大学 2025-01-24 CN claimed
CN-116178092-B Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof 苏州大学 2024-11-22 CN claimed
CN-117430632-A Ortho-bis-quaternary phosphonium salt derivative and preparation method thereof 华东理工大学 2024-01-23 CN claimed
CN-116283659-A Preparation method and application of m-nitrobenzonitrile 上海忝晴化工有限公司 2023-06-23 CN claimed
CN-116178092-A Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof 苏州大学 2023-05-30 CN claimed
CN-113336786-B Diastereoselective polysubstituted naphthenic compound and preparation method thereof 南京工业大学 2022-10-18 CN claimed
CN-111484503-B Mikanolide derivative and preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2022-05-27 CN claimed
CN-113578395-A Pd/Fe-MOFs promote photocatalytic C-N and C-C bonding 重庆工商大学 2021-11-02 CN claimed
CN-102924366-A Carbazole ketone intermediate containing multi-functional group structure and preparation method for carbazole ketone intermediate CHANGCHUN APPLIED CHEMISTRY 2013-02-13 CN claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
JP-2006501159-A 2006-01-12 JP claimed
US-20050234239-A1 Method of forming a carbon-carbon or carbon-heteroatom linkage SHASUN PHARMA SOLUTIONS, INC. 2005-10-20 US claimed
CN-1668595-A Method for forming carbon-carbon or carbon-heteroatom bonds RHONE POULENC CHIMIE (FR) 2005-09-14 CN claimed
EP-1509502-A1 METHOD OF FORMING A CARBON-CARBON OR CARBON-HETEROATOM LINKAGE RHODIA CHIMIE (FR) 2005-03-02 EP claimed
WO-2003101966-A1 METHOD OF FORMING A CARBON-CARBON OR CARBON-HETEROATOM LINKAGE RHODIA CHIMIE (FR) 2003-12-11 WO claimed
EP-0354078-B1 DERIVATIVES OF BENZOCYCLOHEPTENE, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 1993-03-10 EP claimed
EP-0354078-A2 Derivatives of benzocycloheptene, method for their preparation and pharmaceutical compositions containing same ADIR ET COMPAGNIE (FR) 1990-02-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050234239-A1 Method of forming a carbon-carbon or carbon-heteroatom linkage AOC1, AOC3, NUDT1 TRPV1 4005/4885ALDH1A1 436/4885TSHR 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.