SCHEMBL3672506

SCHEMBL3672506

FC(F)(F)C(c1ccc(I)cc1)(c1ccc(I)cc1)C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
TRPV1 Q8NER1 3/20 0.38
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703958 0.87 ESR1 (0.45) ESR1ESR2TRPV1
SCHEMBL10706950 0.87 ESR1 (0.45) ESR1ESR2TRPV1APP
SCHEMBL22694326 0.79 ALDH1A1 (0.50) ESR1ESR2APP
SCHEMBL3672316 0.78 TRPV1 (0.38) ESR1ESR2TRPV1APP
SCHEMBL1229916 0.78 TRPV1 (0.38) ESR1ESR2TRPV1APP
SCHEMBL5354856 0.78 TRPV1 (0.38) ESR1ESR2TRPV1APP
SCHEMBL3677277 0.77 TRPV1 (0.41) ESR1ESR2TRPV1APP
SCHEMBL1616 0.77 TRPV1 (0.55) TRPV1
SCHEMBL25191871 0.74 TRPV1 (0.53) TRPV1
SCHEMBL7929127 0.74 ESR1 (0.59) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0522469-A2 Preparation of poly(benz(ox, imid, thi)azole) polymers EASTMAN KODAK COMPANY (US) 1993-01-13 EP claimed
US-5149755-A Aroatmic amine and halide reactants EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
US-11173484-B2 Anion exchange resin, electrolyte membrane, binder for forming electrode catalyst layer, fuel cell electrode catalyst layer and fuel cell UNIVERSITY OF YAMANASHI (JP) 2021-11-16 US disclosed
US-20200230590-A1 ANION EXCHANGE RESIN, ELECTROLYTE MEMBRANE, BINDER FOR FORMING ELECTRODE CATALYST LAYER, FUEL CELL ELECTRODE CATALYST LAYER AND FUEL CELL UNIVERSITY OF YAMANASHI (JP) 2020-07-23 US disclosed
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
EP-1188807-B1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORP (JP) 2007-10-17 EP disclosed
EP-1099719-B1 Diyne-containing (co) polymer, processes for producing the same, and cured film JSR CORP (JP) 2007-01-17 EP disclosed
US-7153767-B2 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2006-12-26 US disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
EP-1245554-B1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORP (JP) 2005-01-26 EP disclosed
US-20050003218-A1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2005-01-06 US disclosed
EP-0522469-A2 Preparation of poly(benz(ox, imid, thi)azole) polymers EASTMAN KODAK COMPANY (US) 1993-01-13 EP disclosed
US-5149755-A Aroatmic amine and halide reactants EASTMAN KODAK COMPANY (US) 1992-09-22 US disclosed
EP-0192767-B1 DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE Hughes Aircraft Company (US) 1990-05-16 EP disclosed
US-4722985-A Derivatives of diphenylhexafluoropropane and polymers thereof HUGHES AIRCRAFT COMPANY (US) 1988-02-02 US disclosed
US-4719258-A Derivatives of diphenylhexafluoropropane and resins thereof HUGHES AIRCRAFT COMPANY (US) 1988-01-12 US disclosed
US-4649207-A Derivatives of diphenylhexafluoropropane HUGHES AIRCRAFT COMPANY (US) 1987-03-10 US disclosed
EP-0092310-B1 BIS(HALOPHENYL)HEXAFLUOROPROPANES AND PROCESS FOR MAKING THE SAME Hughes Aircraft Company (US) 1985-07-24 EP disclosed
US-4503254-A HALOGENATION OF HYDROXY PRECURSOR WITH TRIPHENYLPHOSPHINE DIHALIDE HUGHES AIRCRAFT COMPANY (US) 1985-03-05 US disclosed
EP-0092310-A1 Bis(halophenyl)hexafluoropropanes and process for making the same Hughes Aircraft Company (US) 1983-10-26 EP disclosed