Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 2/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17075877 | 1.00 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9323738 | 0.98 | LMNA (0.63) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9323407 | 0.92 | LMNA (0.55) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL2991463 | 0.85 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL2988179 | 0.85 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL7287996 | 0.84 | ALDH1A1 (0.46) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL11512364 | 0.84 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL3503210 | 0.84 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4740183 | 0.83 | LMNA (0.63) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4366571 | 0.83 | LMNA (0.63) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533972-A | Polyurethane compositions with low content of monomeric diisocyanates | SIKA技术股份公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-2139936-A1 | ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION | Sika Technology AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008116902-A1 | ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |