SCHEMBL3672508

SCHEMBL3672508

O=S(=O)(c1ccc(Oc2cccc(S(=O)(=O)c3ccc(OS(=O)(=O)C(F)(F)F)cc3)c2)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
PGR P06401 7/20 0.44
NR3C1 P04150 1/20 0.44
AR P10275 1/20 0.44
ESR2 Q92731 1/20 0.44
PTGES2 Q9H7Z7 1/20 0.43
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
SOS1 Q07889 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
PTPN1 P18031 1/20 0.42
ABCC9 O60706 1/20 0.42
ABCC8 Q09428 1/20 0.42
KCNJ11 Q14654 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3677240 0.97 HTT (0.52) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL3679848 0.95 HTT (0.51) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL3671604 0.87 HTT (0.53) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL3676366 0.86 F2 (0.43) HTTSMN1; SMN2PGRNR3C1AR
SCHEMBL5179650 0.84 CA1 (0.50) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL4150360 0.84 HTR6 (0.54) HTTTDP1SMN1; SMN2POLBSOS1
SCHEMBL822779 0.82 PKM (0.50) HTTSMN1; SMN2POLBCA1CA2
SCHEMBL3677390 0.82 HTT (0.59) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL11418604 0.81 HTT (0.68) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL9779108 0.81 HTT (0.56) HTTL3MBTL1TDP1SMN1; SMN2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed